£1.2m Boost for Southampton Research to Personalise Breast Cancer Treatment

£1.2m Boost for Southampton Research to Personalise Breast Cancer Treatment
Machine used to measure body composition. Credit: WCRF - Supplied University of Southampton

By Health Correspondent

A team of cancer scientists and clinicians at the University of Southampton and University Hospital Southampton has received £1.2 million from the World Cancer Research Fund to improve breast cancer treatment.

Led by Professors Ellen Copson and Ramsey Cutress, the researchers will study how body composition – including levels of body fat and muscle – and physical activity affect how patients respond to cancer treatment.

Currently, doctors use simple measurements like weight and height to guide chemotherapy doses.

The team hopes that using detailed body scans and exercise data will help create more personalised and effective treatment plans, reducing side effects and improving outcomes.

The new funding will allow the team to explore how body composition influences patient responses not only to chemotherapy but also to targeted therapies, immunotherapies, and hormonal treatments.

Their research programme, called CANDO (Cancer and Nutrition: Discovering Outcomes), has already collected data from 300 breast cancer patients in Southampton.

The team will now expand the study across seven NHS trusts to include a more diverse group of participants.

Professor Cutress said:

“This funding will help us understand how body composition, exercise, and nutrition affect outcomes and tailor cancer treatments for each individual.”

Professor Copson added:

“Our aim is to make cancer therapies safer and more effective, giving clinicians and patients better information to guide treatment choices.”

Breast cancer remains the most common cancer in women, with over 55,000 new UK cases each year.

Researchers hope that this study will lead to a more personalised approach to cancer care across the NHS within the next decade.

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